Publication

Author

Tian Liu

  1. Lee SY, Kim B, Jeong HK, Min KJ, Liu T, Park JY, Joe EH, Jou I. Enhanced phosphatidylinositol 4-phosphate 5-kinase a expression and PI(4,5)P2 production in LPS-stimulated microglia. Neurochem Int. 2010 Nov;57(5):600-7.

  2. Lee SY, Kim B, Yoon S, Kim YJ, Liu T, Woo JH, Chwae YJ, Joe EH, and Jou I. Phosphatidylinositol 4- phosphate 5-kinase α is induced in ganglioside-stimulated brain astrocytes and contributes to inflammatory responses. Exp Mol Med. 2010 Sep 30;42(9):662-73.

  3. Kang DE, Roh SE, Woo JA, Liu T, Bu JH, Jung AR, Lim Y. The interface between cytoskeletal aberrations and mitochondrial dysfunction in Alzheimer’s Disease and related disorders. Exp Neurobiol. 2011 Jun;20(2):67-8

  4. Liu T, Lee SY. Phosphatidylinositol 4-phosphate 5-kinase a negatively regulates nerve growth factor-induced neurite outgrowth in PC12 cells. Exp Mol Med. 2013 Mar 29;45:e16

  5. Liu T, Roh SE, Woo JA, Ryu H, Kang DE. Cooperative role of RanBP9 and P73 in mitochondria-mediated apoptosis. Cell Death &Disease. 2013 Jan 24;4:e476

  6. Roh SE, Woo JA, Lakshmana MK, Uhlar C, Ankala V, Boggess T, Liu T, Hong YH, Mook-Jung I, Kim SJ, Kang DE. Mitochondrial dysfunction and calcium deregulation by the RanBP9-cofilin pathway. FASEB J. 2013 Dec;27(12):4776-89.

  7. Liu T, Im W, Lee ST, Ban JJ, Chai YJ, Lee M, Mook-Jung I, Chu K, Kim M. Modulation of mitochondrial function by stem cell-derived cellular components. Biochem Biophys Res Commun. 2014 Jun 13;448(4):403-8

  8. Liu T, Im W, Mook-Jung I, Kim M. MicroRNA-124 slows down the progression of Huntington’s disease by promoting neurogenesis in the striatum. Neural Regen Res. 2015 May;10(5):786- 91. doi:10.4103/1673-5374.156978. PubMed PMID: 26109954; PubMed Central PMCID: PMC4468771.

  9. Lee M, Liu T, Im W, Kim M. Exosomes from adipose-derived stem cells ameliorate Huntington’s disease phenotypes in an in vitro model. Eur J Neurosci. 2016 May 14. doi: 10.1111/ejn.1327

  10. Liu T, Lee M, Ban JJ, Im W, Mook-Jung I, Kim M. Cytosolic extract of human adipose stem cells reverses the amyloid beta-induced mitochondrial apoptosis via P53/Foxo3a pathway. PLoS One. 2017 Jan 3 ;12(1) :e0168859

  11. Liu T., Wang F., LePochat P., Woo J A., Bukhari M Z., Hong K W., Trotter C., Kang DE. Cofilin-mediated neuronal apoptosis via P53 translocation and PLD1 regulation. Scientific Reports. 2017, doi:10.1038/s41598-017-09996-3

  12. Woo, J.A, Liu T., Zhao X; Trotter C., Yrigoin K; Cazzaro S ; De Narvaez E., Khan H., Witas R., Bukhari A.,Makati K., Kang D.E*. Enhanced tau pathology via RanBP9 and Hsp90/Hsc70 chaperone complexes. Human Molecular Geneticis. 2017. doi: https://doi.org/10.1093/hmg/ddx284

  13. Woo, J.A*., Liu T*., Trotter C*., Fang C.C., De Narvaez E., LePochat, P., Maslar D., Bukhari A., Zhao X., Deonarine A., Westerheide S.D., Kang D.E. Loss of function CHCHD10 mutations in cytoplasmic TDP- 43 accumulation and synaptic integrity. Nature Communications. 2017. 8: 15558. (* Co-First)

  14. J Lee*, Y Kim*, T Liu*, YJ Hwang, S J Hyeon, K Lee, V E. A, A C. McKee, S Um, M Hur, I Mook-Jung, N W. Kowall and H Ryu. SIRT3 deregulation is linked to mitochondrial dysfunction in Alzheimer’s disease. Aging Cell. 2018 Feb;17(1). doi: 10.1111/acel.12679 (* Co-First)

15. Liu, T *; Woo, J.A, Yan, Y; LePochat, P; Bukhar, M.Z and Kang DE*. Dual Role of Cofilin in APP Trafficking and Amyloid b Clearance. FASEB J. 2019. 33(12):14234-14247.  (*Corresponding)

  1. Woo, J.A., Liu, T., Fang, C.C., Cazzaro, S., Kee, T., Lepochat, P., Yrigoin, K., Trotter, C., Zhao, X., Wang, X., Liggett, S.B., Kang, D.E*. Activated cofilin in tau-mediated microtubule dynamics and tauopathy. Activated cofilin exacerbates tau pathology by impairing tau-mediated microtubule dynamics. Communications Biology .2019. 2: 112. PMCID: PMC6430779.
  2. Liu T *., Woo J.A., Mohammed ZB., Lepochat P., Chacko A., Selenica MB., Yan Y., Kotsiviras P., Buosi SA., Zhao X., Kang D.E*. CHCHD10-regulated Opa1-mitofilin complex mediates TDP-43-induced mitochondrial phenotypes associated with Frontotemporal dementia. FASEB J. 2020.  doi: 10.1096/fj.201903133RR. PMID: 32369233 (*Corresponding)
  3. Woo, J.A., Liu, T., Fang, C.C., Castano, M., Kee, T., Yrigoin, K., Yan, Y., Cazzaro, S.,Matlack, J., Wang, X., Zhao, X., Kang, D.E.*, Liggett, S.B*. β-arrestin2 oligomers impair the clearance of pathological tau and increase tau aggregates. PNAS. 2020.117(9):5006-5015. Doi:10.1073/pnas 1917194117
  4. Fang C., Woo, J.A., Liu T., Zhao X., Cazzaro S., Yan Y., Matlack J., Kee T., LePochat P., Kang D.E. SSH1 impedes p62/SQSTM1 flux and tau clearance independent of cofilin activation. Autophagy. 2021. PMID: 33044112 DOI: 10.1080/15548627.2020.181666
  5. Hyeon SJ, Park J, Yoo J, Kim SH, Hwang YJ, Kim SC, Liu T, Shim HS, Kim Y, Cho Y, Woo J, Kim KS, Myers RH, Ryu HL, Kowall NW, Song EJ, Hwang EM, Seo H, Lee J, Ryu H. Dysfunction of X-linked inhibitor of apoptosis protein (XIAP) triggers neuropathological processes via altered p53 activity in Huntington’s disease. Prog Neurobiol. 2021. Sep;204:102110.doi: 10.1016/j.pneurobio.2021.102110. Epub 2021.Jun 21. PubMed PMID: 34166773; PubMed Central PMCID: PMC8364511.
  6. Liu T*, Woo JA, Bukhari MZ, Wang X, Yan Y, Buosi SC, Ermekbaeva A, Sista A, Kotsiviras P, LePochat P, Chacko A, Zhao X, Kang DE*. Modulation of synaptic plasticity, motor unit physiology and TDP-43 pathology by CHCHD10. Acta Neuropathol Commun. 2022 Jul 4;10(1):95. doi: 10.1186/s40478-022-01386-9. PubMed PMID: 35787294; PubMed Central PMCID: PMC9254494. (*Corresponding)
  7. Woo JA, Yan Y, Kee TR, Cazzaro S, McGill Percy KC, Wang X, Liu T, Liggett SB, Kang DE. β-arrestin1 promotes tauopathy by transducing GPCR signaling, disrupting microtubules and autophagy. Life Sci Alliance. 2022.Mar;5(3). doi: 10.26508/lsa.202101183. Print 2022 Mar. PubMed PMID: 34862271; PubMed Central PMCID: PMC8675912.
  8. Kee TR, Wehinger JL, Gonzalez PE, Nguyen E, McGill Percy KC, Khan SA, Chaput D, Wang X, Liu T, Kang DE, Woo JA. Pathological characterization of a novel mouse model expressing the PD-linked CHCHD2-T61I mutation. Hum Mol Genet. 2022 Nov 28;31(23):3987-4005. doi: 10.1093/hmg/ddac083. PubMed PMID: 35786718; PubMed Central PMCID: PMC9703812.
  9. Alici H, Uversky VN, Liu T, Kang DE, Woo JA, Coskuner-Weber O. Frontotemporal Dementia-Related V57E Mutation Impairs Mitochondrial Function and Alters the Structural Properties of CHCHD10. ACS Chem Neuroscience.2023. DOI: 10.1021/acschemneuro.3c00125. PubMed PMID: 37194187
  10. Cazzaro S, Woo JA, Wang X, Liu T, Rego S, Kee T, Kor Y, Vazquez-Rosa E, Pieper AA, Kang DE. Slingshot homolog-1mediated Nrf2 Sequestration tips the balance from neuroprotection to neurodegeneration in Alzheimer’s Disease. PNAS. 2023. DOI: 10.1073/pnas.2217128120
  11. Liu T*, Wetzel L, Zhu Z, Kumaraguru P, Song S-Y, Gorthi V, Yan Y, Woo JA, Kang DE*. CHCHD10 variants regulate mitophagy through PARL1 and impact TDP-43 accumulation. Cells.2023. 12(24), 2781; https://doi.org/10.3390/cells12242781 (*Corresponding)